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🔍 Usage

You can easily get informations of a paper by passing a PubMed ID:

from aitrika.engine.aitrika import OnlineAItrika
aitrika_engine = OnlineAItrika(pubmed_id=pubmed_id)
title = aitrika_engine.get_title()
print(title)

Or you can parse a local pdf:

from aitrika.engine.aitrika import LocalAItrika
aitrika_engine = LocalAItrika(pdf_path = pdf_path)
title = aitrika_engine.get_title()
print(title)

Breast cancer genes: beyond BRCA1 and BRCA2.

You can get other informations, like the associations between genes and diseases:

associations = aitrika_engine.get_associations()

[
  {
    "gene": "BRIP1",
    "disease": "Breast Neoplasms"
  },
  {
    "gene": "PTEN",
    "disease": "Breast Neoplasms"
  },
  {
    "gene": "CHEK2",
    "disease": "Breast Neoplasms"
  },
]
...

Or you can get a nice formatted DataFrame:

associations = aitrika_engine.associations(dataframe = True)

      gene                          disease
0    BRIP1                 Breast Neoplasms
1     PTEN                 Breast Neoplasms
2    CHEK2                 Breast Neoplasms
...

With the power of RAG, you can query your document:

## Prepare the documents
documents = generate_documents(content=abstract)

## Set the LLM
llm = GroqLLM(documents=documents, api_key=os.getenv("GROQ_API_KEY"))

## Query your document
query = "Is BRCA1 associated with breast cancer?"
print(llm.query(query=query))

The provided text suggests that BRCA1 is associated with breast cancer, as it is listed among the high-penetrance genes identified in family linkage studies as responsible for inherited syndromes of breast cancer.

Or you can extract other informations:

results = engine.extract_results(llm=llm)
print(results)

** RESULTS **

- High-penetrance genes - BRCA1, BRCA2, PTEN, TP53 - responsible for inherited syndromes
- Moderate-penetrance genes - CHEK2, ATM, BRIP1, PALB2, RAD51C - associated with moderate BC risk
- Low-penetrance alleles - common alleles - associated with slightly increased or decreased risk of BC
- Current clinical practice - high-penetrance genes - widely used
- Future prospect - all familial breast cancer genes - to be included in genetic test
- Research need - clinical management - of moderate and low-risk variants
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